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Year : 2015  |  Volume : 18  |  Issue : 1  |  Page : 1-4

Applications of Bacillus subtilis as an important bacterium in medical sciences and human life

1 Department of Infectious Diseases, Infectious and Tropical Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2 Department of Modern Sciences and Technologies, Mashhad University of Medical Sciences, Mashhad, Iran

Correspondence Address:
Dr. Seyed Hossein Shahcheraghi
Infectious and Tropical Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd
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DOI: 10.4103/1119-0388.152530

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Probiotics are a group of organisms without pathogenic effects. These organisms are known as creatures that have advantageous effects on the safety of their host. The most common kinds of microbes that are used as probiotics are Lactic acid bacteria (LAB) and bifidobacteria; but several yeasts and bacteria may also be used. In this study, we have reviewed the benefits of Bacillus subtilis as a probiotic bacterium. The journals published from 1989 to 2012, have been used in the study. At the start of the twentieth century, these organisms were thought to usefully affect their host by ameliorating the intestinal bacterial equilibrium, and therefore, injuncting the toxin-producing organisms and pathogens. Nowadays, particular health effects are being examined and documented, including the prohibition and remedy of pathogen-induced diarrhea, palliation of severe intestinal inflammatory diseases, urogenital infections, and atopic cases. Probiotics are generally used as a division of foods with particularly added active live cultures, including soy yogurt, yogurt or as dietary supplements. B. subtilis strains produce antibiotics and enzymes that are important in both medical and industrial sciences.

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