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 Table of Contents  
Year : 2016  |  Volume : 19  |  Issue : 1  |  Page : 79

Transfusion-transmitted dengue

1 Primary Care Unit, Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Medicine Unit, Faculty of Medicine, University of Nis, Nis, Serbia

Date of Web Publication17-Dec-2015

Correspondence Address:
Somsri Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok
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DOI: 10.4103/1119-0388.172056

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How to cite this article:
Wiwanitkit S, Wiwanitkit V. Transfusion-transmitted dengue. Trop J Med Res 2016;19:79

How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Transfusion-transmitted dengue. Trop J Med Res [serial online] 2016 [cited 2019 Oct 17];19:79. Available from: http://www.tjmrjournal.org/text.asp?2016/19/1/79/172056


The problem of transfusion-transmitted dengue is very interesting. There is a recent case report that can confirm the evidence of transfusion-transmitted dengue in the most real-time situation.[1] In fact, atypical mode of transmission of dengue including transfusion-related transmission has been mentioned for many years.[2] The present concern is on the safety of the present blood product. Screening for the donor should be strictly done. Of interest, in a recent publication by Stramer et al. is the high rate of dengue viremia that could be observed in donated blood.[3] A similar observation is also reported by Linnen et al.[4] They found that “dengue viremia rates among asymptomatic blood donors from 0.30% in Honduras to 0.04% in Brazil.”[4] Screening for dengue in donated blood is the issue that is widely discussed for its cost-effectiveness.[5] In tropical Southeast Asia where dengue is highly endemic, routine screening is still not in use. Indeed, the incubation period of dengue is rather short and the donor who has dengue infection should exhibit some symptoms, such as fever, that should be detectable during blood donation. Sometimes, the practitioners might overlook the complete screening of vital signs of the blood donor before donation. Making sure that the donor is actually asymptomatic is the basic critical step to guarantee safety.

  References Top

Levi JE, Nishiya A, Félix AC, Salles NA, Sampaio LR, Hangai F, et al. Real-time symptomatic case of transfusion-transmitted dengue. Transfusion 2015. [Epub ahead of print].  Back to cited text no. 1
Wiwanitkit V. Unusual mode of transmission of dengue. J Infect Dev Ctries 2009;4:51-4.  Back to cited text no. 2
Stramer SL, Linnen JM, Carrick JM, Foster GA, Krysztof DE, Zou S, et al. Dengue viremia in blood donors identified by RNA and detection of dengue transfusion transmission during the 2007 dengue outbreak in Puerto Rico. Transfusion 2012;52:1657-66.  Back to cited text no. 3
Linnen JM, Vinelli E, Sabino EC, Tobler LH, Hyland C, Lee TH, et al. Dengue viremia in blood donors from Honduras, Brazil, and Australia. Transfusion 2008;48:1355-62.  Back to cited text no. 4
Wilder-Smith A, Chen LH, Massad E, Wilson ME. Threat of dengue to blood safety in dengue-endemic countries. Emerg Infect Dis 2009;15:8-11.  Back to cited text no. 5


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