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Year : 2016  |  Volume : 19  |  Issue : 2  |  Page : 124-127

Study of haematological parameters of lubricating engine oil factory workers and controls in Nnewi, South-East Nigeria

1 Department of Medical Laboratory Science, College of Health Sciences, Nnamdi Azikiwe University, Nnewi, Anambra, Nigeria
2 Department of Haematology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra, Nigeria

Correspondence Address:
John C Aneke
Department of Haematology, Nnamdi Azikiwe University Teaching Hospital, PMB 5025, Nnewi, Anambra State
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DOI: 10.4103/1119-0388.185435

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Background: Products of crude oil, including benzene and its derivatives, exert adverse cytotoxic and suppressive effects on blood cells, particularly the hematopoietic precursors in the bone marrow. Objective: To determine the effect of exposure to lubricating oil on hematological parameters and how these are influenced by alcohol consumption in factory workers in Nnewi, South-East Nigeria. Subjects and Methods: A total of 50 nonsmoking lubricating oil factory workers and 50 apparently healthy nonoil factory workers were recruited for this study. A volume of 3 ml of venous blood was collected from each participant for full blood count, using automated hematology analyzer (PE-6800, Prokan; ). Data were analyzed using the Statistical Package for Social Sciences version 16.0 (SPSS Inc., Chicago IL, USA). The level of statistical significance was P < 0.05. Results: The mean ages of study subjects and controls were 29.00 ± 6.06 and 30.55 ± 5.47 years, respectively (P = 0.37). The means of red blood cell count, hemoglobin concentration, hematocrit, red cell indices and white cell and differential counts were significantly lower in the study subjects than controls (P values all < 0.05). There were no significant differences in parameters at different durations of exposure and between test subjects who consumed alcohol and those who did not. Conclusion: Occupational exposure to lubricating oils appears to suppress hematopoiesis, in a manner that may be independent of the duration of exposure.

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