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REVIEW ARTICLE
Year : 2017  |  Volume : 20  |  Issue : 1  |  Page : 10-15

Zika virus: Docile or deadly?


Department of Infectious Diseases, Shifa College of Medicine, Islamabad, Pakistan

Correspondence Address:
Haider Ghazanfar
Shifa College of Medicine, Pitrus Bukhari Road, H-8/4, Islamabad
Pakistan
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DOI: 10.4103/1119-0388.198098

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Zika virus (ZIKV) has been declared a global public health emergency by the World Health Organization (WHO). The WHO has estimated that 4 million people can be infected by ZIKV by the end of 2016 if proper preventive measures are not taken. Our search results had yielded a total of 373 articles, of which 40 articles were included for perusal. In this review, we highlight the pathogenesis of ZIKV, different modes of transmission of ZIKV, and issues related to the diagnosis of ZIKV. Serological tests have shown strong cross-reactivity of immunoglobulin M against other flaviviruses. We have also highlighted possible preventive steps that can be deployed to prevent the epidemic from getting out of hands. The article also highlights the implication of the forthcoming Summer Olympic Games in Brazil on the spread of ZIKV. With the development of its vaccine still in embryonic stages, proper preventive strategies are the need of the hour.


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